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Description
Treatment for unexplained weight gain often includes lifestyle changes that can reduce weight and maintain a healthier weight moving forward

Constipation or abdominal discomfort: Slowed gastric emptying can sometimes cause digestive changes

Decreased appetite: While beneficial for weight loss, reduced food intake may be challenging for some individuals to manage

Among small-molecule oral GLP-1 candidates, orforglipron is the most clinically advanced and the only one to have completed multiple Phase 3 trials with positive results

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