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Description
Abstract Objective: This study aims to systematically investigate the clinical efficacy and mechanisms of glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1 RAs) in the treatment of knee osteoarthritis (KOA), elucidate their underlying mechanisms, and propose potential future research directions
Semaglutide, an FDA-approved medication, offers a long-term solution for individuals struggling with weight loss management
JAMA Internal Medicine Patient Page: I Am Taking a GLP-1 Weight-Loss Medication What Should I Know

The findings were startling: Regular consumption of sugary drinks was associated with diabetes but so was consumption of diet drinks

Additionally, GLP-1RAs ameliorate DPN through various mechanisms, including the inhibition of inflammation, oxidative stress, and extracellular matrix remodeling, while simultaneously improving neural structure, function, and energy metabolism [11, 12, 30, 7986]
