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GLP-1s claimed the top two spots in 2024 drug spending and accounted for more than one-third of the top 10 drugs overall.

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Despite effectiveness, side effects like nausea and diarrhea are common, and most Americans say they dont plan to take them.

Scientists were chasing an incretin hormone, and when GLP-1 was finally discovered, we found that it had a pronounced satiety effect, slowed down gastric emptying, and actually reduced postprandial insulin response