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Some people microdose as a maintenance strategy, but what your body needs to maintain weight loss may be a standard dose, a lower dose or even a relatively high one

Experiencing a bad taste in your mouth whilst taking GLP-1 medications is an uncommon but recognised side effect that can affect some patients during treatment

For weight management, specific criteria apply as outlined in relevant NICE technology appraisals (such as TA875 for semaglutide 2.4mg), generally requiring a BMI 35 kg/m (or 30 kg/m with weight-related comorbidities), with lower thresholds (typically 2.5 kg/m lower) for people from certain ethnic groups, and treatment within specialist weight management services

Some individuals achieve their weight loss goals and feel best on 1 mg or 1.7 mg, while others benefit from 2.4 mg

doi: 10.1111/nmo.14418