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Blood pressure reduction and major cardiovascular events in people with and without type 2 diabetes

Ko GT, Chan WB, Chan JC, et al

These medications are typically considered when metformin and other treatments haven't achieved adequate glycaemic control, and are usually prescribed within a specific therapy sequence
Recently, the feasibility of using CRISPR/Cas9 to tag endogenous proteins with the very bright luciferase NanoLuc has been demonstrated (White et al., 2017), although the required tags still might interfere with function
