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Individuals consuming under 1,000 kcals/d likely function in a catabolic state and the protein-sparing effect of carbohydrates is lost

This makes them suitable for individuals who are seeking a lifelong solution to maintaining a healthy weight

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Understanding these mechanisms helps patients and healthcare professionals distinguish between benign treatment-related changes and symptoms requiring further investigation

The hippocampus underpins memory formation, the prefrontal cortex governs executive function and attention, and the hypothalamus integrates energy status with neuroendocrine signalingfunctions that are progressively disrupted early in neurodegenerative disease