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The correlation analysis was performed defining the AUC of either early-phase breath hydrogen (60180 min after the start of the test) or second-meal breath hydrogen (210300 min after the start of the test) as the independent variable and the AUC of second-meal desire-to-eat ratings (210300 min after the start of the test) as the dependent variable

Each peak corresponding to the oligomeric DOCAs-linker was purified and lyophilized for further steps

Whether GLP-1R is expressed in IFP adipocytes remains to be explored, but in this eventuality, GLP-1 analogues through anti-inflammatory effects could provide a whole-joint tissue response to OA by also targeting IFP inflammation

Eating a meal within two hours before injection can reduce the GH spike by 60-80%
