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Your weight loss trajectory at 48 weeks will be the same whether you reach your maintenance dose at week 16 or week 28
Improved insulin sensitivity directly reduces the hormonal imbalance that disrupts ovulation

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J Biol Chem (1992) 267:107058

This imbalance can disrupt the HPG axis short for the hypothalamic-pituitary-gonadal axis which links the brain and testes to regulate testosterone levels and sperm production
