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As such, these adulterated variations remain unstudied substitutes

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Whereas the DPP-IV degradation can be avoided by substituting Ala 8 with various amino acids like Gly, Ser, d-Ala, and Aib, 32,37 the degradation by NEP 24.11 is hard to address in a similar manner because of the multiple sites that NEP 24.11 targets (Figure 1)

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