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GLP-1 receptor agonist 7 generates cAMP under the mediation of GLP-1R with an EC 50 of 0.2 nM
& Probstfield, J
GLP-1+GIP dual-agonists - such as tirzepatide - add a second mechanism: mimicking GIP (glucose-dependent insulinotropic polypeptide), which targets additional hormonal pathways involved in appetite and blood sugar regulation
doi: 10.1038/s41588-022-01285-8
