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risks: Early phase 2 data show even the lowest semaglutide dose (0.05 mg/day) drives meaningful weight loss (67% at one year) with fewer GI side effects, and tirzepatide 1 mg/week yields modest A1c and weight reductions with better tolerability

How GLP-1 Medications Quiet the Noise Mounjaro and Wegovy work primarily by mimicking GLP-1 and, in the case of tirzepatide, the GIP hormone as well gut hormones that regulate appetite, slow gastric emptying, and signal satiety to the brain

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