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doi: 10.1530/JME-15-0155

Each addition to your protocol introduces new variables that can affect everything from GI comfort to energy levels to sleep quality

Participants had to have: BMI 40 1 obesity-related comorbidity (OSA, HTN, CVD, dyslipidemia) Documented failure of lifestyle interventions Almost 69% were female , average age 52 years , and mean BMI 46.3

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But recently, the numbers have stopped dropping
