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Across 24 pooled trials with treatment durations from 3 to 12 months, reductions in lean body mass clustered in the 14% range modest, by that metric

The precise mechanism of activating the proliferative pathway via the PI3-kinase pathway is not clear

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Clinical significance, tumor immune landscape and immunotherapy responses of ADAR in pan-cancer and its association with proliferation and metastasis of bladder cancer