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A 2024 pharmacovigilance analysis of a global drug safety database found that GLP-1 receptor agonists, including semaglutide, had reporting-odds ratios suggesting associations with depression, anxiety, and, in rare cases, suicidal ideation

Neurology 73 , 17381745 (2009)

its a direct result of declining oestrogen levels

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Impact of NAD + Biology on Systemic Glucose Metabolism in an Organ-Specific Manner 2.1
