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But sizing the full, eventual impact of these drugs remains difficult, given a large number of unknowns/lingering unanswered questions, and the fast pace of change when it comes to continued clin

There is a unique opportunity for collaboration across specialties to raise awareness around the multiple benefits of GLP-1 RAs and determine the best care pathway to treat patients with PAD. With the ongoing PAD amputation and obesity epidemics, there is an opportunity to establish partnership and open communication between vascular surgeons and weight loss clinics to determine if a patient could benefit from GLP-1 RAs. i Molina CS, Faulk JB

GLP-1 stimulation induced serine phosphorylation of wild-type GLP-1R, which was abolished in all individual doublet as well as triple doublet phospho-null mutants

While weight loss can be beneficial, these widely used drugs come with side effects that arent

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