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Given that UC recurrence causes pain, as well as great financial and psychological pressures, 13,14 it is an increasing burden on public health worldwide

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Fat mass reduction can potentially alter these hormonal pathways, though the net clinical effect varies among individuals

Sleep Optimization Strategies: Maintain consistent bedtime and wake schedules Aim for 7-9 hours of nightly sleep duration Create conducive sleep environments (cool, dark, quiet) Limit screen exposure before bedtime Consider relaxation techniques for improved sleep quality Sleep quality directly impacts energy levels and adaptation capacity, making rest prioritization crucial during treatment initiation and dose adjustments