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Functional analyses demonstrated that i ) DIV-1 is required for the robust proliferation typical of the germline, ii ) loss of DIV-1 enhances and suppresses specific phenotypes that are associated with reduced and elevated GLP-1/Notch activity in germline and somatic tissues, and iii ) DIV-1 works together with FBF/PUF proteins, downstream regulators of GLP-1/Notch signaling, to promote germline stem cell (GSC) maintenance and germline proliferation

New research from Sweden has found that GLP-1 agonist drugs used to treat diabetes and obesity are unlikely to increase thyroid cancer risk, as some previous studies had suggested.

Then, we will discuss the approaches that can increase the endogenous production of GLP-1 through various stimuli

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