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While cross-trial comparisons should always be interpreted cautiously, these results appear to exceed what weve previously seen with semaglutide and tirzepatide alone

However, weight loss with these drugs also could lower risk for obesity-related cancers

Adults with overweight: BMI of 27 or higher with at least one weight-related health condition, such as: Type 2 diabetes High blood pressure Sleep apnea Before starting Wegovy, consult your healthcare provider to ensure it's the right treatment for you

After all, people with obesity have more muscle mass than people without obesity (because their bodies carry more weight), so it's normal to lose muscle when you lose weight whether by diet, exercise, medications, or surgery