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Orbicular Pharmaceutical Technologies has received tentative FDA approval for its generic version of semaglutide, paving the way for commercialization in 2030 as patent exclusivity ends

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Phase 3 titration schedule (246912 mg), missed-dose protocol, taper guidance, and dose-by-dose weight loss data.

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Results Once-a-month single-dose semaglutide microcapsule was developed, which effectively suppressed the initial burst release down to 10%, maintained therapeutic plasma drug concentration for a month, and improved the surface appearance of microcapsules

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