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GLP-1 medications are designed for long-term weight management, not short-term fixes

Over time, lower intake can make it more difficult to get enough protein, fluids, and essential nutrients

Although these mechanisms have been exploited to facilitate weight loss, these medications have also been indicated for patients with cardiovascular or renal diseases, all of which have caused a recent drastic rise in prescribing GLP-1 RAs

Chicory inulin

This Comment highlights emerging evidence and advocates for clinical strategies that prioritize muscle preservation to ensure the long-term success and safety of pharmacological weight management.