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Results : Our NMA of 29 RCTs with 145,895 participants found that only two exendin-4 derivativeslixisenatide and high-dose efpeglenatide (i.e., 6 mg/week)showed increased hearing loss events compared to controls

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While originally developed for blood sugar management, GLP-1 and GIP therapies are now commonly used under medical supervision to support metabolic health, weight management, and body composition in individuals who meet appropriate criteria

People with diabetes have an increased risk of hearing impairment because prolonged elevated blood glucose levels can damage small blood vessels and nerves in the inner ear, independent of diabetes medications

Ehlers Danlos syndrome and gastrointestinal manifestations: A 20-year experience at Mayo Clinic