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On the high-dose sema-bima combination, patients lost exclusivley fat at 24 weeks and 90% fat mass at 48 weeks

Many PlexusDx patients resume compounded semaglutide or tirzepatide once breastfeeding ends, maintaining the weight they achieved and continuing their health trajectory

Efficacy is slightly reduced in those with diabetes, but participants were still able to lose 16.9% of body weight alongside a 2.16% reduction in HbA1c from baseline after 36 weeks [118]

Both medications carry warnings about pancreatitis risk, and Mounjaro commonly causes gastrointestinal side effects such as nausea and vomiting

Enhanced Physical Functioning: Because they are lighter, women with lipedema often experience improved mobility and reduced discomfort during physical activities