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Drawing through the rubber stopper of a vial dulls the tip, and a dull needle hurts more going through skin

Lifestyle intervention of hypocaloric dieting and walking reduces abdominal obesity and improves coronary heart disease risk factors in obese, postmenopausal, African-American and Caucasian women

A few things worth knowing before making that comparison: Compounded drugs are not FDA-approved finished products

In the SURMOUNT-1 trial, participants without diabetes achieved average weight loss of 15-20% of baseline body weight over 72 weeks at the highest doses, with somewhat lower reductions observed in people with type 2 diabetes

Mindful eating is also key
