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These cytokines are sufficient and necessary for inducing both astrocyte transformation into neurotoxic A1 and blood-retina barrier destruction, resulting in the subsequent retinal ganglia cell death and various ophthalmopathy (Guttenplan et al., 2020

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The law also mandated that schools stop marketing the fat-, sugar-, and salt-laden snacks the sugary beverages, the chocolate bars in cafeterias and vending machines, and that they replace those offerings with lower-calorie and more nutritious alternatives like fruit cups and granola bars

10.1016/j.ejphar.2020.173581 92

It has also been tried in patients with heart failure or those who had MASH or with chronic kidney disease
