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Dispose of the needle and syringe safely in a sharps container
Orlistat reduces absorption of fat-soluble vitamins (A, D, E, K), requiring supplementation taken at least 2 hours apart from orlistat (ideally at bedtime)
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Depression or Suicidal Ideation: Topiramate, like many anticonvulsants, carries a warning regarding mood changes and suicidal thoughts

Because the medication reduces hunger drive rather than forcing weight loss, it works best as a tool that makes healthy choices feel easier, not as a replacement for lifestyle shifts
