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In a double-blind clinical trial, individuals taking semaglutide for GLP-1 weight loss in Santee, SC dropped 14.9% of their body weight over 68 weeks.

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Genetic factors in peptide signaling pathways, combined with biomarker monitoring and provider oversight, can help identify who may experience persistent effects versus those who tolerate treatment well over time

74% female) underwent standardized LSG and was followed for five years with annual measurements of weight, BMI, %TWL, %EWL, GLP-1 and GIP
