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GLP-1 receptor agonists are prescribed off-label for weight loss in non-diabetic adults with obesity or overweight status plus weight-related comorbidities

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These medications exert (in)direct hepatic actions by reducing steatosis, attenuating inflammation, and potentially reversing fibrosis, while simultaneously addressing systemic metabolic abnormalities including excessive obesity, insulin resistance, and cardiovascular risk

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Yellow Persistent or worsening patterns such as poor intake, recurring nausea, training decline, or function getting harder