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The results from the sensitivity analyses accounting for either the full population of SURPASS2 (sensitivity analysis 1), the full population of both trials (sensitivity analysis 2), the treatmentregimen estimand in the full population of both trials (sensitivity analysis 3) or the adjusted baseline HbA1c and body weight in the full population of both trials (sensitivity analysis 4) were consistent with those of the primary analysis (Figure 2A)

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Lee PG, Cigolle CT, Ha J, Min L, Murphy SL, Blaum CS, Herman WH

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For example, the benefits for overweight/obese individuals were highlighted in the SURMOUNT-1 trial, which involved overweight/obese individuals with an average weight of 104.8 kg and a BMI of 38.0, indicating that tirzepatide could be a new option for weight loss in this specific population