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However, newer GLP-1 medications, such as tirzepatide, which target both GLP-1 and GIP receptors, may be even more effective for weight loss

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Bottom line Tirzepatide (Mounjaro, Zepbound) and semaglutide (Ozempic, Wegovy, Rybelsus) are used to treat conditions such as Type 2 diabetes and sleep apnea and are also often used for weight loss (whether FDA-approved or off-label)

It is also made by the same company that made dulaglutide, making it their modern competitor to semaglutide

Clinical studies show patients lose an average of 20 to 25 percent of their body weight on tirzepatide the strongest results among all GLP-1 options available today