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Oprah has used WeightWatchers for years, but even more recently Oprah has opened up about holistic weight management and taking weight loss medication as a part of that program

After 24 h incubation, fibroblasts were fixed with 4% (w/v) paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with QuickBlock Blocking Buffer (Beyotime, Shanghai, China), and incubated with ASC antibody (1:400, Cell Signaling Technology, Danvers, MA, USA, 67824s) at 4 overnight

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Hanna Lee, MD, an endocrinologist at Northwells Lenox Hill Hospital

Common issues include: Nausea and vomiting Diarrhea or constipation Abdominal pain or "sulfur burps" For a deeper dive into managing these symptoms, see our guide on Managing GLP-1 Side Effects