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Description
However, a study in Obesity cited a lack of evidence for the effectiveness of other OTC supplements

Tirzepatide has a half-life of approximately 5 days

GLP-1 (glucagon-like peptide-1) is released from the gut after eating

Medications maintain therapeutic drug levels continuously, whereas food-stimulated GLP-1 secretion occurs in pulses after meals and is rapidly degraded

As a result, obesity poses a ~30% increased risk for all-cause death for every five kg/m 2 increase in body mass index (BMI) and remains an unmet area of clinical and public health need 3
