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Abstract Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome with various phenotypes, and obesity is one of the most common and clinically relevant phenotypes of HFpEF

Depending on the PubMed search strategy, GLP-1 receptor agonists return thousands of randomized-trial citations across diabetes, obesity, renal, cardiovascular, and metabolic outcomes
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[DOI] [PMC free article] [PubMed] [Google Scholar] 84.Glucagon-like peptide-1 modulates RAW264.7 macrophage polarization by interfering with the JNK/STAT3 signaling pathway

SURMOUNT-1: Tirzepatide Once Weekly for Obesity (NEJM, 2022) 2.Fras et al
