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Aldhaleei et al., for instance, found increased gastrointestinal (GI) adverse events in GLP-1RA users, which could contribute to nocturnal reflux and sleep disruption [17]

Focus on nutrient-dense foods like eggs, chicken, fish, beans, tofu, whole grains, fruits, vegetables, nuts, seeds, and healthy fats

High BMI: If you ultimately need 2 mg semaglutide or 10 mg tirzepatide, microdosing adds 6-12 months of sub-therapeutic costs

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There is also the issue of price pressures from both public health systems and private insurers as the GLP-1 class continues to grow and more generic versions are introduced