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42 Likewise, a systematic review of 41 studies involving overweight or obese participants showed a significant reduction in total-hip BMD (0.0100.015 g/cm 2 ) after weight-loss interventions lasting six months or longer, whereas lumbar-spine BMD remained stable
Storage and cold-chain integrity is a third documented failure category
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Dose increases should only happen when nausea is mild or has mostly resolved
