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For many people, the stomach has a thicker layer of subcutaneous fat and fewer nerve endings than the thigh

Now they are known to be of a different type but able to bind various psychotropic agents

doi:10.1016/j.jaad.2025.07.017 Oberlin KE

Semaglutide acts on GLP-1 receptors in the brain and gut to slow stomach emptying, increase feelings of fullness, and signal the pancreas to release insulin when blood sugar rises
