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The fact that real-world results come within a few percentage points of trial data speaks to tirzepatide's robust efficacy even under imperfect conditions

In some cases, these side effects can be severe enough to lead to dehydration or even kidney failure

Tirzepatide (Zepbound) for weight loss The bottom line Tirzepatide (Zepbound) was approved in 2023 by the US Food and Drug Administration (FDA) for weight loss

Lifestyle modifications during treatment create the foundation for whatever maintenance approach you ultimately pursue

Importantly, tirzepatide carries a boxed warning for thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)