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Serial sections of GLP-1R-immunoreactive DRG immunostained with no peptide (A) or with 1 g peptide (B), 100 ng peptide (C), 10 ng peptide (D), 1 ng peptide (E) or 100 pg peptide (F)

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And here is the important part: if you miss two or more consecutive doses, you may need to restart the full titration schedule from 0.25 mg to avoid severe gastrointestinal side effects

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BMJ 359 , j4849 (2017)

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A second important avenue is drug repurposing : the targeted re-evaluation of existing medicines based on the new mechanism

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