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Short Bowel Patients Treated for Two Years With Glucagon-Like Peptide 2: Effects on Intestinal Morphology and Absorption, Renal Function, Bone and Body Composition, and Muscle Function

In preclinical models, comparison of cotadutide, a glucagon/GLP-1 dual RA, and liraglutide demonstrated superior reduction of hepatic de novo lipogenesis and enhancement of hepatocyte mitochondrial oxidative capacity (similar to levels stimulated by glucagon mono-agonismsuggesting restoration of mitochondrial function is a glucagon-specific benefit) [39]

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They also help improve insulin sensitivity 7 , making it easier for your body to metabolize glucose instead of storing it as fat

As a glucagon-like peptide-1 (GLP-1) receptor agonist, semaglutide mimics the action of the GLP-1 hormone in the body