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It appears to represent a recalibration of the brain's reward and satiety circuitry, reducing the hedonic drive to eat independently of hunger signals

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As metabolic hormones emerge as modulators of craving and compulsion, the artificial boundaries between mind and body, psychology and physiology, begin to dissolve

ACE2 and diabetic complications

Muscles are important in both type 2 diabetes and obesity, and muscle mass is also directly correlated with life expectancy," says Tore Bengtsson, professor at the Department of Molecular Bioscience, Wenner-Gren Institute, Stockholm University