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The higher your dose of a medication, the more intense the symptoms youll experience

Warfarin and other drugs with a narrow therapeutic index (such as digoxin): The absorption of orally administered medicines can be affected due to slowing of gastric emptying (as with GLP-1 RAs), and so monitoring at initiation of tirzepatide and following dose escalation is recommended

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However, if patients experience severe redness, swelling, or notice other symptoms like diarrhea, they should contact their healthcare provider

Retatrutide achieved 82% liver fat reduction in Phase 2a trials, far exceeding what tirzepatide or semaglutide achieve