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Tirzepatide is a dual-agonist , meaning it works by targeting two hormones: GLP-1: helps regulate appetite, blood sugar, and digestion GIP: supports insulin response and reduces nausea Retatrutide is a triple-agonist , meaning it targets three hormones: GLP-1: helps regulate appetite, blood sugar, and digestion GIP: supports insulin response and reduces nausea Glucagon: affects energy use and fat metabolism Early studies show that retatrutide may be more successful than tirzepatide at managing diabetic kidney disease, as well as for weight control, while tirzepatide may be better at managing blood glucose

[116] To mitigate lean mass loss, recommendations include resistance training (e.g., squats, lunges, weights) 23 times per week, focusing on compound movements and progressive overload to target major muscle groups, alongside aerobic exercise aiming for 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity activity per week

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Keep sealed: Store vials away from light, moisture, and frequent temperature changes