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REIMAGINE 2 was a 68-week efficacy & safety trial investigating once weekly SC CagriSema, a fixed-dose combination of the Amylin receptor agonist, cagrilintide, & GLP-1RA, Semaglutide, compared to Semaglutide & placebo, the study enrolled 2,728 patients with type 2 diabetes inadequately controlled with metformin with or without an SGLT2I

The FDA sent a warning letter this month to Novo Nordisk, alleging the drugmaker failed to report, in a timely manner, potential side effects in patients who took its popular medications containing semiglutide.