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For more info on constipation causes and treatment check out Cleaveland Clinic Does constipation go away on GLP-1

2013 Jan;9(1):27-36

Clinical trial results showed that participants experienced 15% to 18% weight loss during the trials

Conversely, if you're tolerating your medication well but seeing no progress, simply waiting it out rarely solves the problemstrategic intervention through titration or alternative compounds works better

Approval for Sleep Apnea, MASH, CKD Tirzepatide (Zepbound) originally approved for weight loss now also holds FDA approval for the treatment of moderate to severe obstructive sleep apnea in adults with obesity