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For example, while GLP-1 RAs carry a low intrinsic risk of hypoglycemia, the addition of a GLP-1 RA to background sulfonylurea or insulin therapy can increase the risk for treatment-emergent hypoglycemia

Skipping doses disrupts this, which can lead to rebound appetite and withdrawal-like symptoms

This unique mechanism gives cagrilintide a distinct role in weight loss regimens, especially when combined with GLP-1 receptor agonists

Their once-weekly dosing and favorable safety profile further enhance adherence and adoption

That means researchers were not running a randomized clinical trial where they assign drugs
