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Description
Our dual-plasmid DNA system comprised a Cas9 expression DNA and an sgAlb-E14 expression DNA containing the donor sequence (Fig

PsA Disease Activity Improves on GLP-1s A retrospective study presented at ACR Convergence 2025, led by researchers from the University of Toronto and NYU, followed 48 patients with psoriatic arthritis who started GLP-1 receptor agonists. The findings: Significant weight loss (35% of patients lost 510% of body weight
And indeed not only safe, but in fact cardioprotective, based on the SELECT trial

GLP-1 is primarily produced by specialised L-cells in the intestine, which release the hormone in response to food intake

GLP-1 is mainly produced in the enteroendocrine L cells located in the distal intestine exerting its effects through binding to the GLP-1 receptors (GLP-1R) expressed in the pancreas, heart, blood vessels, gastrointestinal tract (GIT), kidney, lung, breast, and central nervous system [11],[12]