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HMSC transduced with lentiviral vectors to overexpress Ex-4 (MSC-Ex-4) maintained typical hMSC morphology, viability, and surface marker expression (CD44, CD73, CD90, and CD105), indicating that the genetic modification did not compromise stemness or core phenotypic characteristics [18, 26]

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This condition affects roughly 5% of Americans and is more common in women over 60