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such potential mechanisms include the anti-inflammatory effects of GLP-1RAs on various pathways [48]
The maintenance study FIGARO UC 303 (NCT03290781) enrolled 366 responders who continued their induction dose or switched to placebo for 52 weeks, demonstrating that both 25mg and 75mg doses significantly outperformed placebo with clinical remission rates of 53.5% and 40.2% respectively versus approximately 8-13% placebo, while inclusion criteria required patients aged 1866 years with moderate to severe disease and the completed studies showed favorable safety profiles with most common adverse events being UC worsening, arthralgia, and nasopharyngitis (51)

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Learn more about how Semaglutide regulates appetite, promotes fat loss and supports long-term weight loss in Canton, Georgia

For genetically predisposed individuals, this reversal feels especially strong because their baseline appetite is naturally elevated
