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How Semaglutide Injections Damage Blood Vessels When a needle penetrates the skin during a semaglutide injection, it can puncture small blood vessels (capillaries) in the subcutaneous tissue layer

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First, it includes a large, unselected cohort representative of routine clinical practice

In one notable example, the company rejected a CAPA request related to burnt electrodes with air pockets, despite the nonconformance potentially causing "arcing and burning a patient." The rejection was justified because it was "the first-time instance of such an event," even though the issue carried significant patient risk