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However, current evidence does not strongly justify the cessation of GLP-1 RAs based on suicidality concerns

eClinicalMedicine (2024)

This treatment resulted in a significant reduction in mean PASI and DLQI scores, improved skin lesions, and reduced levels of interleukin (IL)17, IL-23, and tumor necrosis factor alpha (TNF)

All we're proposing to clinicians is Hey, think about the patients who are at risk and have a strategy to monitor and mitigate that risk." In a secondary analysis, the scientists found that weight loss alone did not explain the increased risk, suggesting other mechanisms of action may be at play