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To view or add a comment, sign in The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a Science study from earlier this year in mice

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Less common but documented risks include pancreatitis, gallbladder disease, and acute kidney injury

These side effects typically diminish as the body adjusts, but understanding what to expect helps patients prepare rather than panic

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